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ApoB to ApoA1 Ratio and Cardiovascular Risk
All NiaHealth tests are processed in Canadian-certified labs, which are highly trusted by the medical community for their accuracy and reliability. Blood and urine samples are collected by licensed medical professionals and processed using state-of-the-art equipment. NiaHealth is SOC2 Type 2 certified.
What is it?
The ApoB/ApoA1 ratio tells us what the relative concentration of particles that cause atherosclerosis and those that protect against it are in your blood.
Why it matters
Researchers looking at the risk of cardiovascular disease in over 30,000 people found that the ratio of ApoB to ApoA1 in the blood was one of the most significant predictors of heart disease and stroke.
Reference ranges
In general, it is better to have lower levels of ApoB and higher levels of ApoA1. Therefore lower levels of the ApoB/ApoA1 ratio are better. We have based our at risk and optimum cut off values based on the levels at which cardiovascular risk appears to change significantly.
Tikkanen, Emmi, et al. "Metabolic biomarker discovery for risk of peripheral artery disease compared with coronary artery disease: lipoprotein and metabolite profiling of 31 657 individuals from 5 prospective cohorts." Journal of the American Heart Association 10.23 (2021): e021995.
Walldius, Goran, and I. Jungner. "The apoB/apoA‐I ratio: a strong, new risk factor for cardiovascular disease and a target for lipid‐lowering therapy–a review of the evidence." Journal of internal medicine 259.5 (2006): 493-519.
This information is educational and does not replace medical advice, diagnosis, or treatment. Your results should be interpreted with a qualified healthcare professional in the context of your health history.
