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The 50+ biomarker panel
Our clinical team carefully selected these tests to provide a full view of your health. All tests listed are included in the Plus and Optimum plans (50+ tests), while those marked with a blue dot (•) are in the Essential plan (35 tests). Tests labeled "Add-on" can be purchased separately.
Lipoprotein(a) or Lp(a) is a type of LDL cholesterol molecule with an additional protein called apolipoprotein(a). Elevated levels of Lp(a) in the blood are considered an independent risk factor for heart diseases, such as coronary artery disease and aortic valve stenosis.
Apolipoprotein B100 (ApoB) is a protein that marks problematic cholesterol-carrying particles, such as LDL. Elevated concentrations of these particles indicate a higher risk of artery-clogging events, making it a significant marker for cardiovascular risk.
Low-density lipoprotein-cholesterol (LDL-c) is a measure of cholesterol content carried by atherogenic particles in the body. While cholesterol is essential for building cells and certain hormones, when deposited in artery walls, it can create inflammation and narrowing of blood vessels thereby increasing the risk of cardiovascular events like heart attacks and strokes.
High-density lipoprotein cholesterol (HDL-c) is the cholesterol concentration found within high-density lipoprotein molecules, which play a vital role in removing cholesterol from the bloodstream. These particles act as a cleaner of blood vessels and are thought to be protective against heart disease.
Non-high-density lipoprotein cholesterol (non-HDL-c) measures the cholesterol content in all atherogenic particles. It gives insight into the risk of arterial buildup of cholesterol making it an important measure for heart disease risk.
Triglycerides are a kind of fat in the blood. High levels, especially in combination with other lipid imbalances, may heighten the risk of cardiovascular diseases.
Total cholesterol is a measurement that quantifies the sum of all types of cholesterol in the bloodstream and is used in the calculation of non-HDL-c. Measuring total cholesterol is a common part of lipid panels and provides a broad overview of an individual's cholesterol profile. No specific ranges or parameters are necessary for this collective marker.
hs-CRP, or high-sensitivity C-reactive protein, is a marker indicating inflammation in the body. Elevated levels suggest increased inflammation which can be a risk factor for heart disease. Various factors, including infections, injuries, and chronic inflammation, can influence hs-CRP levels.
Uric acid is produced during the breakdown of purines, substances found in certain foods and drinks. High levels in the blood can lead to conditions like gout or kidney stones. Factors influencing uric acid include diet, kidney function, and certain genetic factors.
Hemoglobin is a protein in red blood cells that carries oxygen. Low levels suggest anemia. Iron status, bone marrow health, and hydration can affect hemoglobin values.
RBC, or Red Blood Cell count, indicates the number of oxygen-carrying cells. Abnormal counts can suggest anemia or hydration issues. Factors influencing RBC include bone marrow function and overall health.
Hematocrit (HCT) shows the portion of blood made of red blood cells. It provides insight into oxygen-carrying capacity. Dehydration, lung health, and bone marrow function can influence HCT values.
Mean corpuscular volume (MCV) measures the average size of red blood cells. It is key for classifying types of anemia. Bone marrow function and iron status play roles in MCV levels.
Mean Corpuscular Hemoglobin Concentration (MCHC) gauges the average concentration of hemoglobin in red blood cells. It is used in anemia diagnosis. Factors affecting MCHC include iron status and bone marrow health.
Red blood cell distribution width (RDW) indicates the variation in red blood cell size. It is used to diagnose and classify anemia. Bone marrow function and iron status can influence RDW.
WBC, or White Blood Cell count, measures immune cells in the blood. High or low levels can suggest infections or other conditions. Immune function, bone marrow health, and certain diseases can affect WBC values.
Platelets are small blood cells vital for clotting. Abnormal counts can suggest bleeding disorders or certain diseases. Bone marrow function, immune health, and certain conditions can influence platelet counts.
Neutrophils are white blood cells crucial for fighting bacterial infections. Abnormal levels can suggest infections, inflammation, or other conditions. Factors include immune responses, certain medications, and bone marrow health.
Lymphocytes play a role in the body's immune response, targeting viruses and cancers. Abnormal counts can indicate viral infections or immune disorders. Immune health, certain diseases, and bone marrow function can influence lymphocyte levels.
Monocytes are white blood cells that become macrophages, essential for fighting infections. Elevated or reduced levels can hint at chronic inflammation or certain diseases. Factors influencing monocyte counts include immune function and overall health.
Eosinophils fight parasites and are involved in allergic reactions. High counts can suggest allergies or parasitic infections. Allergic conditions, certain medications, and immune responses can impact eosinophil levels.
Basophils are involved in allergic responses. Elevated levels are rare but can suggest certain blood disorders. Allergies, immune function, and certain conditions can influence basophil counts.
nRBC, or nucleated Red Blood Cells, are immature RBCs. Presence in the bloodstream can hint at bone marrow stress or diseases. Bone marrow health and certain conditions can impact nRBC presence.
Blasts are immature blood cells. Elevated levels in the bloodstream can be a sign of certain blood cancers. Factors influencing blasts include bone marrow function and specific diseases.
Creatinine is a byproduct of muscle metabolism. Elevated levels in the blood can indicate impaired kidney function, as the kidneys are responsible for its filtration and excretion. Factors influencing creatinine include muscle mass, age, and kidney health.
eGFR, or estimated Glomerular Filtration Rate, is a measure of kidney function. A low eGFR indicates that the kidneys may not be filtering the blood effectively. It is calculated using age, sex, creatinine levels, and other factors.
Urea is a waste product formed from protein breakdown. Elevated blood urea levels can suggest reduced kidney function, as kidneys play a role in its removal. Dietary protein intake, hydration status, and kidney function can influence urea levels.
The urine albumin-to-creatinine ratio (ACR) test is a diagnostic tool used to assess kidney function and detect signs of kidney damage, particularly related to conditions like diabetes and high blood pressure.
Alanine aminotransferase (ALT) is an enzyme found in the liver. Elevated ALT levels in the blood can indicate liver damage or inflammation. Factors like alcohol consumption, medications, or certain diseases can impact ALT levels.
Aspartate aminotransferase (AST) is another enzyme originating from the liver and some other organs. Elevated levels can signal liver injury or other tissue damage. Various factors, including liver health, medications, and alcohol, can influence AST values.
Alkaline phosphatase (ALP) is an enzyme linked to the liver and the bones. High levels can suggest liver disease or bone disorders. Age, bone growth, and liver health are among the factors affecting ALP.
Gamma glutamyl transferase (GGT) is a liver enzyme. An increase in its levels often points to liver disease or bile duct issues. Alcohol consumption and certain medications can also raise GGT levels.
Total bilirubin is derived from the breakdown of red blood cells (RBCs). High levels can cause jaundice and suggest liver dysfunction or certain types of anemia. Factors like liver health and rapid RBC breakdown influence bilirubin levels.
Albumin is a significant protein the liver produces. Decreased levels can hint at liver or kidney disorders, or malnutrition. The state of liver function and nutritional status play a role in determining albumin levels.
TSH regulates thyroid function. Abnormal levels can suggest a thyroid that is overactive or underactive. TSH levels are influenced by the pituitary gland's response to thyroid hormone levels.
Magnesium is a mineral vital for muscle, nerve, and enzyme functions. Imbalanced levels can lead to muscle cramps or cardiac issues. Dietary intake, kidney health, and certain medications can affect magnesium levels.
Vitamin B12 is essential for nerve function and DNA formation. Deficiency can result in fatigue and neurological issues. B12 levels are influenced by diet, absorption efficiency, and certain medications.
Ferritin is a protein that stores iron. Low levels typically indicate iron deficiency, while high levels might suggest inflammation or iron overload. Factors like iron intake, inflammation, and certain conditions can impact ferritin values.
Iron is a crucial mineral for producing red blood cells. Imbalances can lead to conditions like anemia or iron overload. Dietary intake, absorption rates, and blood loss influence iron levels.
TIBC measures the blood's capacity to bind iron. Elevated TIBC often indicates iron-deficiency anemia. Factors affecting TIBC include iron status and liver function.
The saturation index indicates the percentage of iron-binding sites occupied by iron. It is crucial for diagnosing iron-related disorders. Iron levels and TIBC values determine the saturation index.
Folate is a B-vitamin necessary for DNA synthesis. It is especially important to maintain at optimal levels in pregnancy. Dietary intake and absorption rates play roles in folate levels.
Hemoglobin A1c, or A1c provides a snapshot of average blood sugar levels over the past 2-3 months. It is a key indicator of diabetes management and risk. Factors that can influence A1c levels include blood sugar control, diet, and medication adherence.
Fasting plasma glucose measures blood sugar levels after an overnight fast. It is a primary tool for diagnosing diabetes. Elevated levels can indicate the body's inability to regulate sugar effectively. Diet, pancreatic function, and insulin sensitivity play roles in determining these levels.
Fasting insulin levels give insight into how much insulin the body is producing when you have not eaten. Elevated levels can suggest insulin resistance, a precursor to diabetes. Factors that influence fasting insulin include diet, activity level, and overall metabolic health.
*Only available for in-clinic draws
Calcium is vital for bone health and muscle function. Imbalances can suggest bone disorders or issues with the parathyroid gland. Factors include dietary intake, vitamin D levels, and kidney function.
Phosphate is essential for energy production and bone health. Abnormal levels can point to kidney disease or calcium metabolism issues. Dietary intake, kidney health, and parathyroid function influence phosphate levels.
Vitamin D helps in calcium absorption and bone health. Low levels can lead to bone loss or other disorders. Sun exposure, diet, and absorption rates can affect vitamin D levels.
Testosterone is a sex hormone that plays a key role in supporting bone health, density and strength as well as libido and sexual function. Testosterone is primarily produced by the testes in males and, to a lesser extent, by the ovaries in females. 98% of testosterone is found bound to carrier proteins (sex-hormone binding globulin (SHBG) and to a lesser degree albumin). Between 1-3% is free, unbound testosterone. Total testosterone measures the testosterone that is biologically active (bound to albumin, but not SHBG) along with that which is inactive.
Free testosterone refers to the portion of testosterone in the bloodstream that is not bound to proteins, such as sex hormone-binding globulin (SHBG) or albumin. This form of testosterone is considered the active form because it can easily enter cells and exert its biological effects. Free testosterone is a crucial factor in various bodily functions, including libido, muscle mass maintenance, bone density, and mood regulation. While total testosterone levels are essential, free testosterone levels provide a more accurate representation of the hormone's availability for cellular uptake, utilization and better correlates with signs and symptoms.
Luteinizing hormone (LH) is a hormone produced by the pituitary gland that regulates reproductive health, the menstrual cycle, and ovulation in females.
Follicle-stimulating hormone (FSH) helps promote the growth and development of eggs in females and the control of estrogen. In menopause, follicle-stimulating hormone (FSH) levels typically rise as ovarian function declines.
Estradiol is the primary form of estrogen in the body, and it plays a role in the regulation of the female reproductive system. It contributes to the development and maintenance of female reproductive tissues, influences the menstrual cycle, and has effects on various organs and tissues, including the breasts and bones.
Human chorionic gonadotropin (B-HCG) is a hormone used most commonly in detecting pregnancy. As women move into perimenopause and menopause ovulation, and therefore the period of fertility, becomes less predictable. It is important to rule out pregnancy as the cause of missed periods. Other disease states can also produce B-hCG; therefore, elevated levels in menopausal women who are not pregnant require further investigation.
Progesterone (P4) is an endogenous steroid and progestogen sex hormone involved in the menstrual cycle. The main function of progesterone is to prepare the endometrium (lining of your uterus) for a fertilized egg to implant and grow.
Consult a healthspan-focused clinician
Our clinicians focus on prevention and how to optimize healthspan - rather than on treating the complaint of the day or managing an acute illness.
Our clinicians routinely assess biomarkers from a preventive as opposed to diagnostic lens, seeking indicators of one's healthspan - rather than testing based only on symptoms.
Our clinicians attempt to provide detailed lifestyle interventions and personalized strategies as prescriptions - rather than general guidelines for you to follow, helping you take action quicker and more strategically than you may otherwise be able to.
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